NUCLEAR THERAPY PROCEDURES

NUCLEAR THERAPY PROCEDURES

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sinoviortesi

hiper

cdtbaix

CAT-TerapiaSino

RADIOISOTOPE TREATMENT OF SYNOVITIS IN INFLAMATORY CHRONIC ARTHROPATHIES

ENDOCAVITARY RADIOISOTOPE TREATMENT

DESCRIPTION: Treatment of synovitis due to chronic inflammatory arthropathies.

PREPARATION: Treatment is done in agreement with the doctor who indicates it (rheumatologist, traumatologist, systemic illnesses specialist, etc.) and once he/she has established that there are no local contraindications (backed-up with X-rays, IRM or TC if necessary).

INDICATIONS: Treatment of synovitis due to chronic inflammatory arthropathies, such as rheumatoid arthritis and other arthropathies resistant to medical treatment (seronegative arthropathy, hemophilia, villonodular synovitis). Possibility of treating chronic degenerative arthropathy.

DURATION OF PROCEDURE: 30 minutes.

CAT terapia02

RADIOISOTOPE TREATMENT OF HYPERTHYROIDISM

DESCRIPTION: Treatment of hyperthyroidism with I-131.

PREPARATION: If the patient’s clinic allows it, the antithyroid treatment must be withdrawn 7 days before the treatment. In severe hyperthyroidism or in cases of cardiological involvement, it is not necessary to remove the antithyroid treatment. The β-blockers are maintained (on demand). A thyroid blood analysis (total T4 and T3, free T4, TSH and antithyroid antibodies) must be performed as well as routine blood count checks before administering the dose. A pregnancy test must be performed to fertile-age women, which must be negative. A control of therapeutic efficacy by whole-body scan and SPECT/CT must be performed on the fifth day after the treatment. Patients who do not reach euthyroidism without antithyroid treatment at 3 months will be assessed to receive a new dose of I-131 with the same protocol. In the case of recurrence of disease, the same protocol is followed.

INDICATIONS: Treatment of Basedow disease (diffuse goiter). Treatment of multinodular goiter. Treatment of toxic adenoma.

DURATION OF PROCEDURE: 1 hour.

CAT terapia03

RADIOISOTOPE TREATMENT OF
DIFFERENTIATED LOW-RISC
THYROID CANCER
(REMNANTS ABLATION)

DESCRIPTION: Treatment of differentiated low-risk thyroid cancer with I-131.

PREPARATION: The antithyroid treatment must be withdrawn 4 weeks before the treatment or else, rhTSH stimulation must be done. A thyroid blood analysis (with basal and stimulated thyroglobulin measurements) and a regular blood count must be performed before administering the dose. A pregnancy test must also be done to fertile-age women, which must be negative. A control of therapeutic efficacy by whole-body scan and SPECT/CT must be performed on the fifth day after the treatment. Patients who do not achieve ablation can repeat the treatment 6 months later under the same protocol. In case of recurrence, the same protocol is followed.

INDICATIONS: Treatment of differentiated low-risk thyroid cancer.

DURATION OF PROCEDURE: 1 hour.

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dolorossi

policitema

zevalin

CAT terapia04

RADIOISOTOPE TREATMENT OF METASTATIC BONE PAIN WITH STRONTIUM-89 (METASTRON), SAMARIUM-153 (QUADRAMET) AND RADIUM-223 (XOFIGO)

DESCRIPTION: Treatment of pain produced by bone metastasis of prostate or breast carcinoma, resistant to hormone therapy, chemotherapy or analgesics

PREPARATION: No previous preparation is needed.

INDICATIONS: Treatment of bone pain produced by bone metastases of prostate or breast cancer resistant to chemo and hormone therapy or to analgesics. To receive treatment the patient must:

  • Presence of pain caused by bone metastases, coinciding the location of the pain with images compatible with metastasis in a bone scintigraphy. The Karnofsky Index must be 60 or higher. Patients with lower numbers may receive treatment, although in these cases the response is not so favorable.
  • Presence of pain despite regular treatment with opioid or non-opioid analgesics.
  • Patient’s must have preservation of his/her renal function and a hematological function with platelets counts greater than 100 x 109/L and leukocytes counts greater than 3 x 109/L.

DURATION OF PROCEDURE: 15 minutes.

CAT terapia05

RADIOISOTOPE TREATMENT OF POLYCYTHEMIA VERA AND ESSENTIAL THROMBOCYTHEMIA

DESCRIPTION: Treatment of polycythemia vera and essential thrombocytosis with P-32 in the form of sodium phosphate.

PREPARATION: No preparation is required. Childbearing-age women with the possibility of being pregnant must not be subjected to this treatment.

INDICATIONS: Erythrocytosis not controlled by phlebotomies. Excessive thrombocytosis, with platelet counts over 800,000 per cubic mm. Extramedullary hematopoiesis with splenic pain, hypersplenicity, abdominal pain or splenic infarction. Cardiovascular pathology in which repeated phlebotomies are contraindicated. Persistent symptoms, such as pruritus or hyperuricemia not controlled by phlebotomy, antihistamines or allopurinol.

DURATION OF PROCEDURE: 15 minutes.

CAT terapia06

LYMPHOMA TREATMENT WITH ZEVALIN

DESCRIPTION: Treatment and induction to remission of follicular non-Hodgkin’s lymphoma of B CD20 + cells in relapse or refractories to treatment with Rituximab. Zevalin combines the targeted capability of an anti CD20 monoclonal antibody with the cytotoxic potential of yttrium-90 to destroy tumor cells (Ibritumomab, Tiuxetan).

PREPARATION: No special preparation needed. In patients with very low platelet counts, the dose should be reduced.

INDICATIONS: Follicular no-Hodgkin lymphoma of B CD20 + cells in relapse or refractory to treatment with Rituximab.

DURATION OF PROCEDURE: 4 hours.

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visita1

visita2

CAT terapia09

SPECIALIST’S HOME VISIT

DESCRIPTION: Home visit by one of our Nuclear Medicine specialists.

PREPARATION: None. Previous medical reports and medication, if any,  must be at hand.

INDICATIONS: Visit to patients receiving metabolic therapy for hyperthyroidism, bone pain, sinoviortesis or other specific reasons.

CAT terapia08

SPECIALIST’S EMERGENCY HOME VISIT

DESCRIPTION: Emergency home visit by one of our Nuclear Medicine specialists.

PREPARATION: None. Previous medical reports and medication, if any,  must be at hand.

INDICATIONS: Visit to patients receiving metabolic therapy for hyperthyroidism, bone pain, sinoviortesis or other specific reasons.

RADIOISOTOPE TREATMENT OF SYNOVITIS
IN INFLAMATORY CHRONIC ARTHROPATHIES

ENDOCAVITARY RADIOISOTOPE TREATMENT

DESCRIPTION

Treatment of synovitis due to chronic inflammatory arthropathies.

PREPARATION

Treatment is done in agreement with the doctor who indicates it (rheumatologist, traumatologist, systemic illnesses specialist, etc.) and once he/she has established that there are no local contraindications (backed-up with X-rays, IRM or TC if necessary).

INDICACIONES

  • Treatment of synovitis due to chronic inflammatory arthropathies.

  • Treatment of rheumatoid arthritis or other arthropathies resistant to medical treatment (seronegative arthropathy, hemophilia, villonodular synovitis).

  • Possibility of treating chronic degenerative arthropathy.

DURATION OF PROCEDURE

30 minutes.

RADIOISOTOPE TREATMENT OF HYPERTHYROIDISM

DESCRIPCIÓN

Treatment of hyperthyroidism with I-131.

PREPARATION

  • If the patient’s clinic allows it, the antithyroid treatment must be withdrawn 7 days before the treatment. In severe hyperthyroidism or in cases of cardiological involvement, it is not necessary to remove the antithyroid treatment.

  • The β-blockers are maintained (on demand).

  • A thyroid blood analysis (total T4 and T3, free T4, TSH and antithyroid antibodies) must be performed as well as routine blood count checks before administering the dose.

  • A pregnancy test must be performed to fertile-age women, which must be negative.

  • Therapeutic efficacy control by means of whole-body scan and SPECT/CT must be performed on the fifth day after treatment.

  • Patients who do not reach euthyroidism without antithyroid treatment at 3 months will be assessed to receive a new dose of I-131 with the same protocol. In the case of recurrence of disease, the same protocol is followed.

INDICATIONS

  • Treatment of Basedow disease (diffuse goiter).

  • Treatment of multinodular goiter.

  • Treatment of toxic adenoma.

DURACIÓN DEL PROCEDIMIENTO

1 hora.

RADIOISOTOPE TREATMENT OF
DIFFERENTIATED LOW-RISC
THYROID CANCER
(REMNANTS ABLATION)

DESCRIPTION

Treatment of differentiated low-risk thyroid cancer with I-131.

PREPARATION

  • The antithyroid treatment must be withdrawn 4 weeks before the treatment or else, rhTSH stimulation must be done.
  • A thyroid blood analysis (with basal and stimulated thyroglobulin measurements) and a regular blood count must be performed before administering the dose.
  • A pregnancy test must also be done to fertile-age women, which must be negative.
  • A control of therapeutic efficacy by whole-body scan and SPECT/CT must be performed on the fifth day after the treatment.
  • Patients who do not achieve ablation can repeat the treatment 6 months later under the same protocol.
  • In case of recurrence, the same protocol is followed.

INDICATIONS

Treatment of differentiated low-risk thyroid cancer.

DURATION OF PROCEDURE

1 hour.

RADIOISOTOPE TREATMENT OF
METASTATIC BONE PAIN WITH
STRONTIUM-89 (METASTRON),
SAMARIUM-153 (QUADRAMET)
AND RADIUM-223 (XOFIGO)

DESCRIPTION

Treatment of pain produced by bone metastasis of prostate or breast carcinoma, resistant to hormone therapy, chemotherapy or analgesics.

PREPARATION

No previous preparation is needed.

INDICATIONS

Treatment of bone pain produced by bone metastases of prostate or breast cancer resistant to chemo and hormone therapy or to analgesics. To receive treatment the patient must:

  • Presence of pain caused by bone metastases, coinciding the location of the pain with images compatible with metastasis in a bone scintigraphy. The Karnofsky Index must be 60 or higher. Patients with lower numbers may receive treatment, although in these cases the response is not so favorable.
  • Presence of pain despite regular treatment with opioid or non-opioid analgesics.
  • Patient’s must have preservation of his/her renal function and a hematological function with platelets counts greater than 100 x 109/L and leukocytes counts greater than 3 x 109/L.

DURATION OF PROCEDURE

15 minutes.

RADIOISOTOPE TREATMENT OF
POLYCYTHEMIA VERA AND
ESSENTIAL THROMBOCYTHEMIA

DESCRIPTION

Treatment of polycythemia vera and essential thrombocytosis with P-32 in the form of sodium phosphate.

PREPARATION

  • No preparation is required.

  • Childbearing-age women with the possibility of being pregnant must not be subjected to this treatment.

INDICATIONS

  • Erythrocytosis not controlled by phlebotomies.

  • Excessive thrombocytosis, with platelet counts over 800,000 per cubic mm.

  • Extramedullary hematopoiesis with splenic pain, hypersplenicity, abdominal pain or splenic infarction.

  • Cardiovascular pathology in which repeated phlebotomies are contraindicated.

  • Persistent symptoms, such as pruritus or hyperuricemia not controlled by phlebotomy, antihistamines or allopurinol.

DURATION OF PROCEDURE

15 minutes.

LYMPHOMA TREATMENT WITH ZEVALIN

DESCRIPTION

Treatment and induction to remission of follicular non-Hodgkin’s lymphoma of B CD20 + cells in relapse or refractories to treatment with Rituximab. Zevalin combines the targeted capability of an anti CD20 monoclonal antibody with the cytotoxic potential of yttrium-90 to destroy tumor cells (Ibritumomab, Tiuxetan).

PREPARACIÓN

  • No special preparation needed.

  • In patients with very low platelet counts, the dose should be reduced.

INDICATIONS

Follicular no-Hodgkin lymphoma of B CD20 + cells in relapse or refractory to treatment with Rituximab.

DURATION OF PROCEDURE

4 hours.

SPECIALIST’S HOME VISIT

DESCRIPTION

Home visit by one of our Nuclear Medicine specialists.

PREPARATION

  • None.
  • Previous medical reports and medication, if any,  must be at hand.

INDICATIONS

Visit to patients receiving metabolic therapy for:

  • Hyperthyroidism
  • Bone pain
  • Sinoviortesis
  • Other specific reasons

SPECIALIST’S EMERGENCY HOME VISIT

DESCRIPTION

Emergency home visit by one of our Nuclear Medicine specialists.

PREPARATION

  • None.
  • Previous medical reports and medication, if any,  must be at hand.

INDICATIONS

Visit to patients receiving metabolic therapy for:

  • Hyperthyroidism
  • Bone pain
  • Sinoviortesis
  • Other specific reasons
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Josep Irla & Bosch Street, 5-7, Basement, Barcelona 08034, Catalonia, Spain
(+34) 93 204 6439 & (+34) 93 254 0470 Fax (+34) 93 204 9641 info@simm.barcelona

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Logo-SIMM-Largo

Carrer Josep Irla & Bosch, 5,7, Basement, Barcelona 08034, Catalonia, Spain
Phones (+34) 93 204 6439 & (+34) 93 254 0470 Fax (+34) 93 204 9641
Email info@simm.barcelona

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